VC

Phystech Ventures

Niche focus:
Next-gen computing, Life sciences, Energy, Mobility, and Space
Address:
145 City Road. London, England EC1V 1AA, GB
Overview

Phystech Ventures is an early-stage deeptech VC dedicated to fueling the next generation of scientific breakthroughs.

Size of investment
Funding stage

Seed and Series A

Visit website

About Phystech Ventures

Phystech Ventures is a leading deeptech venture capital fund focused on supporting the next generation of scientific breakthroughs. The firm specialises in backing deeptech startups that use core scientific advancements to deliver disruptive solutions and transform entire industries. Phystech Ventures is committed to accelerating innovative technologies by investing in founders who leverage fundamental science to solve complex problems and create significant impact across global markets.

Mission, Goals, and Values

Phystech Ventures’ mission is to advance scientific progress and nurture transformational innovation by investing in deeptech companies that address complex global challenges. The firm is dedicated to enabling exceptional founders whose work leverages fundamental science to develop innovative solutions with the potential to redefine industries and improve the quality of life worldwide. Phystech Ventures strives to serve as a catalyst for groundbreaking technologies that create lasting value for society and the global economy.

Goals

Phystech Ventures aims to:

  • Identify and support entrepreneurial teams developing science-driven technologies with the capacity to deliver disruptive impact across global markets.
  • Accelerate the commercialisation of pioneering scientific research, providing strategic guidance, operational expertise, and introduction to a global network of partners and investors.
  • Bridge the gap between academia and industry, helping founders translate scientific breakthroughs into scalable, market-ready solutions.
  • Foster a vibrant deeptech ecosystem by collaborating with leading research institutions, corporate partners, and fellow investors who share a commitment to advancing scientific innovation.
  • Deliver lasting value for founders, investors, and wider society by supporting companies whose solutions offer meaningful, measurable benefits for people, industries, and the environment.

Values

Phystech Ventures’ core values are anchored in scientific excellence, integrity, and forward thinking. The firm champions transparency and open dialogue in all its partnerships, believing that trust and shared purpose are essential for solving complex challenges. Phystech Ventures prioritises long-term impact over short-term gains, supporting companies whose technologies have the potential to drive real progress and sustainable value. The team encourages curiosity, creativity, and daring within its culture, maintaining the highest standards of ethics and accountability throughout its operations and investment decisions.

Founders and Origin Story

Phystech Ventures was founded in 2013 by Petr Lukyanov and Olga Maslikhova, who shared a vision of bridging the gap between scientific research and commercial innovation. Petr Lukyanov, the firm’s managing partner and co-founder, has a strong background in investment analysis and fund management, previously serving as Investment Director at the Skolkovo Foundation and Ruvento Ventures. Olga Maslikhova, also a co-founder, brings significant experience in early-stage investments and technology transfer, with a particular focus on deeptech sectors such as mobility and IoT. Together, they set out to build a venture capital firm dedicated to supporting science-driven startups and accelerating their path to market.

The founders recognised early on that many of the world’s most promising technologies emerge from academic research but often lack the capital and strategic support to scale. Phystech Ventures was established to address this gap by investing in technologically complex, early-stage companies and providing them with expert guidance and access to a global network. Their combined expertise and long-term commitment have shaped Phystech Ventures into a notable player in deeptech investment, focused on creating lasting impact through science-based innovation.

Explore the founders professional journeys: Petr Lukyanov, Olga Maslikhova.

Investment Focus

Phystech Ventures invests in early-stage companies developing deeptech innovations that leverage fundamental scientific advancements to create transformative solutions. The firm’s primary objective is to back technologies with the potential to disrupt existing markets and address complex global challenges through scientific excellence.

Geographic Scope

Phystech Ventures invests in startups across multiple countries, with a strong presence in Europe, North America, and Asia. The firm actively supports spin-offs from leading universities and research institutions worldwide, providing founders with access to a global network of investors, industry experts, and corporates.

Sectors of Interest

Phystech Ventures focuses on deeptech sectors where core science unlocks new capabilities, including:

  • Next-generation computing such as artificial intelligence, quantum computing, and cybersecurity
  • Life sciences and biotechnology
  • Energy innovations, including clean and sustainable technologies
  • Mobility solutions and space technologies

Investment Criteria

To be considered for investment, companies must:

  • Demonstrate breakthrough scientific innovation with the potential for significant market disruption
  • Have a credible business model and a plan for commercialisation
  • Be at the seed or Series A stage, often as university spin-offs or early ventures
  • Align with Phystech Ventures’ mission of advancing scientific entrepreneurship and creating lasting impact
  • Show potential for long-term growth and scalability across global markets

These criteria ensure Phystech Ventures supports pioneering deeptech companies capable of delivering transformative technological and societal impact alongside commercial success.

Assessment

Phystech Ventures follows a thorough, multi-stage assessment process to identify and invest in the most promising deeptech startups. The process begins with an initial review of the company’s scientific innovation, the founding team’s expertise, and the feasibility of the technology. Founders are expected to demonstrate a strong technical foundation alongside a clear vision for commercialisation.

Once the initial screening is complete, Phystech Ventures engages directly with the founders to evaluate the technology’s readiness, market potential, and strategic fit. This includes detailed discussions on the business model, growth plans, and funding requirements.

For opportunities that advance, Phystech Ventures conducts comprehensive due diligence, which covers scientific validation, market analysis, financial projections, legal review, and assessment of scalability. The investment committee then reviews all findings to confirm alignment with the fund’s mission of supporting science-based entrepreneurship and delivering both commercial and societal impact.

Phystech Ventures also consults external technical and sector experts when necessary to validate complex aspects of the technology and market positioning. This rigorous approach ensures investments are well-founded and positioned for long-term success within the deeptech ecosystem.

Notable Portfolio Companies

Phystech Ventures has built a portfolio of pioneering deeptech startups developing breakthrough technologies across next-generation computing, life sciences, energy, mobility, and space. Each company is selected for its long-term potential to drive technological transformation and create significant global impact.

ZeroAvia

ZeroAvia is a leader in hydrogen-electric propulsion for aviation, developing zero-emission powertrains to replace traditional aircraft engines. The company is working to enable cleaner, quieter, and more economical flight, with hydrogen-electric engines targeting both retrofit and new airframes. Visit ZeroAvia.

Osome

Osome is a platform providing digital business management solutions, including accounting, incorporation, and corporate compliance. Osome leverages automation and AI to support entrepreneurs and SMEs in managing business operations worldwide, with a strong presence in Singapore and the UK. Visit Osome.

MEL Science

MEL Science creates immersive, hands-on STEM education kits and content for children, delivering safe, interactive science experiments and AR/VR-enabled learning experiences at home. Phystech Ventures’ investment has supported MEL Science in scaling globally as digital education surges in demand. Visit MEL Science.

Funding Sources

Phystech Ventures is supported primarily by private investors, including experienced entrepreneurs, venture capitalists, and high net worth individuals. Many of its backers have strong ties to scientific and academic communities, particularly alumni from leading technical universities. The firm’s investor base includes prominent technology founders and venture professionals from multiple countries, reflecting its international reach.

The fund raises capital mainly through private venture capital vehicles, with Phystech Ventures I being its flagship fund. It focuses on early-stage deeptech companies and operates across Europe, North America, and Asia. The firm frequently co-invests alongside other venture funds and family offices, leveraging a blended funding approach to maximise support and follow-on opportunities for portfolio companies.

Phystech Ventures does not rely on public sector or government funding programmes but instead draws on commercially driven private capital. Its extensive network of investors and scientific partners helps source deals, provide expertise, and mobilise additional capital to accelerate portfolio growth.

Investment Details

Stages
Phystech Ventures focuses on early-stage investments, primarily at the seed and Series A stages. The firm supports startups from initial market entry through early growth and scaling phases.

Equity
Investments are typically made on an equity basis. Deal sizes generally range from around $100,000 to $1 million, depending on the company’s stage and capital requirements.

Funds
Phystech Ventures manages venture capital funds dedicated to deeptech sectors, including its flagship Phystech Ventures I fund. These funds target breakthrough scientific innovations across sectors such as next-generation computing, life sciences, energy, mobility, and space.

Recent Developments
Phystech Ventures continues to invest regularly, supporting a portfolio of startups developing transformative technologies. Recent investments include participation in seed and Series B rounds across multiple countries and sectors, demonstrating the firm’s commitment to advancing early-stage deeptech companies globally.

Impact

Phystech Ventures is committed to generating measurable social and environmental impact alongside strong financial returns. The firm focuses on backing deeptech companies whose scientific innovations address pressing global challenges and contribute to sustainable development. Phystech Ventures actively supports responsible business practices within its portfolio, encouraging companies to adopt high standards of governance, sustainability, and ethical conduct.

The firm assesses impact by aligning its investments with key global goals, supporting technologies that promote societal benefits such as clean energy, advanced healthcare, and efficient resource use. Phystech Ventures aims to back companies that create lasting value for both the economy and society, ensuring innovations lead to positive change on a global scale.

Community

Phystech Ventures fosters a collaborative and engaged community of founders, investors, and scientific experts. It brings together a network of industry professionals, academic partners, and venture capitalists who share a dedication to advancing scientific entrepreneurship and deeptech innovation. The firm organises events, workshops, and forums that encourage knowledge sharing, deal collaboration, and mentorship.

Additionally, Phystech Ventures works closely with its portfolio companies, providing ongoing strategic support and access to a broad network of partners and co-investors. This active community approach nurtures innovation and helps startups overcome challenges on their path to commercial success, creating a vibrant ecosystem that advances breakthrough technologies for global impact.

The Team

Phystech Ventures is led by a skilled management team with deep expertise in venture capital, scientific innovation, and startup development. The leadership combines strong backgrounds in investment management and deeptech sectors to support founders in scaling breakthrough scientific ventures globally.

Key Leadership:

  • Daniel Shaposhnikov – Managing Partner
    Daniel co-founded Phystech Ventures in 2013 and leads the AI/ML, energy, and mobility investment verticals. He is known for his operational support to portfolio companies, helping with fundraising, sales strategy, and network expansion. Daniel is also a co-founder and former CEO of HyPoint, a hydrogen startup acquired by ZeroAvia in 2022. He holds qualifications in quantum computing from MIT and MIPT and mentors startups through the Alchemist Accelerator.
  • Ivan Protopopov – Managing Partner and CEO
    Ivan co-founded the firm and brings over a decade of experience in venture capital and private equity. He oversees Life Sciences and SpaceTech investment pipelines and focuses on later-stage investments. Ivan is known for his educational contributions, having authored a deep-dive course on VC funding instruments to train emerging fund managers.

Learn more about the team on the Phystech Ventures people page.

FAQs

  1. What is Phystech Ventures’ investment strategy?
    Phystech Ventures focuses on investing in early-stage deeptech companies that leverage scientific breakthroughs to develop transformative technologies. The firm targets startups with the potential to disrupt industries and address complex global challenges through fundamental science. Its strategy prioritises supporting visionary founders and projects that can scale internationally and deliver both commercial success and lasting societal impact.
  2. What sectors does Phystech Ventures invest in?
    Phystech Ventures invests across several deeptech sectors, including next-generation computing (such as AI, quantum computing, and cybersecurity), life sciences and biotechnology, energy innovations, mobility solutions, and space technologies. The firm targets areas where scientific advancement enables new capabilities and market opportunities.
  3. What does Phystech Ventures look for in founders?
    Phystech Ventures seeks founders with deep scientific expertise who are passionate about commercialising breakthrough innovations. The firm values strong technical knowledge combined with the ability to build scalable businesses. Founders who demonstrate resilience, vision, and a clear path to market fit are prioritised.
  4. What stage does Phystech Ventures invest in?
    Phystech Ventures primarily invests at the pre-seed, seed, and Series A stages, often being the first institutional investor in science-driven startups. It supports companies that have moved beyond concept validation and are focused on product development and early commercialisation.
  5. What is the typical investment size?
    Phystech Ventures typically invests between $100,000 and $1 million in its portfolio companies, depending on the stage and capital needs. Investment sizes are adapted to support scientific development, market entry, and scaling ambitions.

Contact

Are you a deeptech founder developing breakthrough scientific innovations in next-generation computing, life sciences, energy, mobility, or space? Discover how Phystech Ventures can support your journey by visiting Phystech Ventures Website.

Stay connected and receive the latest updates on investments, portfolio companies, and industry insights by following Phystech Ventures on LinkedIn: Phystech Ventures LinkedIn.

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