EIS and SEIS Fund

Qubis Innovation Fund

Niche focus:
Digital, Life science and Environmental
Address:
63 University Road Belfast BT7 1NF
Overview

The QUBIS Innovation Fund is an SEIS & EIS fund, aimed specifically at funding university spin–out companies.

Size of investment

Between £50k and £150k

Funding stage

Pre-seed

Visit website

About Qubis Innovation Fund

QUBIS Innovation Fund is a Belfast based early stage venture capital fund established by QUBIS Ltd, the commercialisation arm of Queen’s University Belfast. The fund specialises in investing in pre seed and seed stage companies emerging from the university and other research partners. With a strong regional focus, QUBIS Innovation Fund backs innovative start ups and scale ups that address key challenges in areas such as health, sustainable growth, education, climate, and security. The team combines deep investment expertise with strong connections to leading academic institutions, supporting science based and technology driven businesses that deliver both commercial success and positive societal impact.

Mission, Goals, and Values

QUBIS Innovation Fund’s mission is to enable entrepreneurial researchers and drive positive commercial and societal change by investing in and supporting early-stage, science-based businesses. The fund is dedicated to building a vibrant innovation ecosystem by backing companies that deliver measurable impact for communities and the economy, while generating sustainable, long-term growth.

Goals:

QUBIS Innovation Fund aims to:

  • Identify and invest in high-potential university spin-outs and start-ups that offer scalable solutions to pressing challenges, including health, engineering, sustainable development, and digital transformation.
  • Foster innovation and responsible entrepreneurship through strategic mentoring, operational support, and access to a collaborative academic and investor network.
  • Support the expansion and commercial scaling of ventures that meet rigorous criteria for innovation, impact, and viability in their markets.
  • Build strong partnerships within the Northern Irish and wider UK innovation ecosystem to promote knowledge sharing, deal flow, and co-investment opportunities.
  • Deliver both societal and financial returns, ensuring investments create lasting positive impact for researchers, communities, and shareholders.

Values:

QUBIS Innovation Fund’s values centre on integrity, accountability, and long-term stewardship. The fund believes commercial success and social impact go hand in hand, investing only in companies whose business models produce tangible benefits for society and the economy. Internally, QUBIS promotes a culture of transparency, collaboration, and inclusivity, united by a shared commitment to responsible investment. The fund holds itself to high standards of governance and ethical principles, ensuring discipline and purpose inform every decision.

Founders and Origin Story

QUBIS Innovation Fund was established by QUBIS Ltd, the commercialisation arm of Queen’s University Belfast, in Belfast. The fund originated from Queen’s University’s ambition, dating back to 1984, to translate pioneering academic research into successful businesses that drive economic and societal benefit. Led by founders and senior managers within QUBIS, including experienced university technology transfer and venture professionals, QUBIS Innovation Fund was created to provide critical early-stage investment and commercial guidance for university spin-outs and research-led start-ups.

QUBIS’s founding team has a strong legacy in Northern Ireland’s innovation ecosystem, with decades of expertise in licensing, technology transfer, and company formation. Notable figures include the team behind QUBIS Ltd itself, whose leadership pioneered spin-out creation and venture support at Queen’s University, helping launch over 100 science-based companies across sectors such as software, life sciences, engineering, and digital technologies. Their professional journeys bring together research commercialisation, startup investment, strategic mentoring, and governance experience.

Under the stewardship of this experienced team, QUBIS Innovation Fund partners with researchers and entrepreneurs to build scalable, innovative businesses that generate measurable societal and economic impact. The fund’s long-term commitment is shaped by deep connections to Queen’s University and the broader research community. This foundation guides QUBIS Innovation Fund’s focus on sustainable growth, ethical governance, and responsible investment, ensuring that every venture supported aligns with the University’s mission to deliver positive change for Northern Ireland and beyond.

Investment Focus

QUBIS Innovation Fund invests in early-stage companies developing innovative technologies and solutions that emerge from Queen’s University Belfast and its partner institutions. The fund focuses on ventures that address significant commercial and societal challenges, with particular emphasis on life sciences, artificial intelligence, engineering, physical sciences, and sustainable technologies. Its core objective is to support businesses that translate pioneering academic research into scalable, market-ready products and services, delivering measurable impact for the economy and society while achieving sustainable, profitable growth.

Geographic Scope:
QUBIS Innovation Fund primarily invests in companies based in Northern Ireland and across the wider United Kingdom. While its focus is on ventures with a strong regional presence and growth potential, many supported businesses have solutions with global relevance and the capacity to scale internationally.

Sectors of Interest:
QUBIS Innovation Fund invests across areas that leverage deep technology and scientific expertise, prioritising ventures with potential for high impact and long-term value creation.

Key areas include:

  • Life sciences and health technology: Innovations improving healthcare outcomes and enabling advanced diagnostics or therapeutics
  • Artificial intelligence and digital technologies: Solutions enhancing efficiency, data-driven decision-making, and digital transformation
  • Engineering and physical sciences: Applied technologies addressing industry challenges and creating competitive advantage
  • Sustainable growth and clean technology: Products and processes that contribute to net zero goals, environmental sustainability, and responsible resource use

Investment Criteria

To be considered for investment, companies must meet the following criteria:

  • Be university spin‑out or research‑led start‑up businesses originating from Queen’s University Belfast or other partner academic and research institutions
  • Be based in Northern Ireland or the wider United Kingdom, with the potential for broader national or international market expansion
  • Have a credible and defensible business model underpinned by innovative science or technology with demonstrable commercial applications
  • Operate at pre‑seed or seed stage, with a clear pathway to product‑market fit and scalable growth
  • Exhibit strong potential for societal and economic impact, consistent with QUBIS Innovation Fund’s mission to translate academic innovation into real‑world solutions
  • Fall within QUBIS’s investment stage and funding parameters, typically qualifying for SEIS or EIS investment, and be capable of meeting rigorous due diligence standards

Assessment

QUBIS Innovation Fund follows a structured, multi‑stage assessment process to identify and invest in early stage, research‑led companies with strong commercial potential and measurable societal and economic impact.

The process begins with an initial evaluation of the company’s technology, intellectual property position, business model, market opportunity, and alignment with QUBIS’s mission to translate academic innovation into real‑world solutions. Founders are expected to demonstrate the scientific or technological validity of their proposition, a clear route to product‑market fit, and a credible growth pathway suitable for pre‑seed or seed stage investment.

Following this, QUBIS works closely with the founding team to understand strategic priorities, operational capabilities, and the potential for the innovation to address market needs at scale. The fund assesses each opportunity against its criteria for innovation quality, commercial viability, and positive societal or environmental contribution, ensuring proposals meet rigorous due diligence and ethical investment standards.

If the opportunity advances, QUBIS conducts in‑depth due diligence covering technical validation, market analysis, financial modelling, intellectual property protection, and legal considerations. This includes assessing scalability, competitive positioning, and the potential economic and community benefits, with input sought from sector specialists, investors, or relevant academic experts to test assumptions and validate impact potential.

Finally, the proposal is reviewed by QUBIS’s investment committee, which evaluates all findings to ensure alignment with the fund’s stage parameters, mission, and risk‑return expectations. This disciplined, collaborative approach ensures QUBIS backs ventures with clear market opportunity, innovation excellence, and capacity for long‑term value creation, supported by the fund’s strategic guidance, operational support, and strong links to the Queen’s University innovation ecosystem.

Notable Portfolio Companies

QUBIS Innovation Fund invests in early-stage spin-out and start-up companies emerging from Queen’s University Belfast and partner institutions, supporting ventures with science-based innovation that offer commercial growth and positive societal impact. Some of the most notable portfolio companies include:

Amply Discovery Ltd
Amply Discovery is a life sciences company developing AI-powered platform technologies to accelerate drug discovery and development. Their scalable solutions are designed to improve healthcare outcomes and efficiency, aligning with QUBIS’s focus on health technology innovation and societal benefit. Visit Amply Discovery

Causeway Sensors Ltd
Causeway Sensors develops advanced sensor technology for environmental and industrial applications, enabling precise monitoring and data collection to support cleaner and more efficient processes. Their innovations contribute to sustainability goals, embodying QUBIS’s commitment to net zero and environmental impact. Visit Causeway Sensors

Nuada Ltd
Nuada is a leading carbon capture company dedicated to helping decarbonise hard-to-abate sectors through its next-generation, ultra-energy-efficient capture technology. Nuada’s systems deploy advanced solid adsorbents and vacuum swing technology to efficiently remove CO₂ from industrial emissions, paving the way for zero carbon operations. Their solutions support the green transition in industries such as cement, steel, and chemicals, directly contributing to the UK’s net zero goals. Visit Nuada

Discover more successful investments: Qubis Innovation Fund portfolio.

Funding Sources

QUBIS Innovation Fund is primarily supported by private capital raised from a network of local investors, including Queen’s University Belfast alumni, regional angel investors, and private equity partners. The fund was initially launched in 2021 with a capital raise of approximately £1.2 million, drawing significant contributions from the Queen’s alumni community and other committed investors focused on supporting university spin-outs based in Northern Ireland.

The capital is deployed into early-stage, research-led spin-out companies emerging from Queen’s University Belfast and partner institutions, with typical investments ranging from £50,000 to £150,000. QUBIS Innovation Fund acts mainly through minority equity positions, providing not only funding but also strategic mentoring, operational guidance, and strong governance support via board representation to enhance portfolio company development.

Unlike traditional venture capital funds, QUBIS Innovation Fund operates as a SEIS and EIS eligible fund, offering tax reliefs to qualifying investors and aligning investment decisions with rigorous due diligence and impact criteria. The fund’s governance and investment standards emphasise commercial viability, innovation quality, and positive societal and economic impact within Northern Ireland and the wider UK innovation ecosystem.

QUBIS Innovation Fund does not publicly cite government or public sector grant funding as a material source of its capital. Instead, it leverages private sector investment combined with the commercialisation and institutional support offered by Queen’s University Belfast through QUBIS Ltd and partnerships such as Sapphire Capital Partners, which manages the fund.

This private capital model, focused on early-stage technology commercialisation, underpins QUBIS Innovation Fund’s mission to build a thriving research-based innovation ecosystem that generates enduring economic and societal returns in Northern Ireland and beyond.

Investment Details

QUBIS Innovation Fund focuses on early stage investments, targeting primarily pre seed and seed rounds. The fund works with companies that have developed innovative, research based technologies and are positioned to achieve initial market entry and early commercial growth.

Equity:
QUBIS Innovation Fund typically invests on an equity basis with deal sizes ranging from £50,000 to £150,000 per company. It takes minority positions, often acting as lead or co-investor, while providing board representation, strategic mentoring, and operational guidance to support portfolio companies’ growth and scaling plans.

Funds:
The fund was launched in 2021 with an initial raise of around £1.2 million, supported by Queen’s University Belfast alumni, private investors, and regional partners. It operates as a SEIS and EIS qualifying vehicle, ensuring investors can benefit from UK tax incentives while providing vital early stage capital to university spin outs with strong growth potential.

Recent Developments:
In 2022 QUBIS Innovation Fund launched a second Innovation Investment Fund in partnership with Sapphire Capital Partners LLP to continue supporting high potential spin outs from Queen’s University Belfast. Notable portfolio companies include Amply Discovery, an AI driven life sciences company accelerating drug discovery; Causeway Sensors, which develops precision sensing technology for environmental and industrial applications; and Nuada, a climate technology company pioneering next generation carbon capture for heavy industry. The fund continues to focus on scaling research led enterprises that can deliver sustainable commercial success and positive societal impact.

Impact

QUBIS Innovation Fund is committed to generating measurable societal and economic impact alongside sustainable commercial returns. The fund embeds responsible investment principles across its selection, due diligence, and portfolio management processes, focusing exclusively on ventures whose innovations deliver tangible benefits to communities, the economy, and, where applicable, the environment. Its mission‑led approach ensures that every investment supports the translation of high‑quality academic research into real‑world solutions that address significant market and societal needs.

QUBIS Innovation Fund measures impact by tracking the achievements of its portfolio companies against clearly defined objectives, such as job creation, revenue growth, knowledge transfer, and contributions to priority sectors including health, sustainable growth, and environmental sustainability. Where relevant, these outcomes are considered in the context of the United Nations Sustainable Development Goals (SDGs), ensuring portfolio alignment with globally recognised impact frameworks. The fund works closely with founders to ensure progress is monitored using verifiable data, maintaining transparency and accountability across the investment lifecycle.

The fund adopts a selective investment policy, avoiding companies or activities that conflict with its mission or ethical standards, such as those that could cause environmental harm, compromise public health, or undermine societal wellbeing. QUBIS also supports portfolio companies in adopting strong governance practices, diversity objectives, and responsible business conduct, fostering a culture of entrepreneurial integrity that enhances long‑term value creation and strengthens Northern Ireland’s innovation ecosystem.

Community

QUBIS Innovation Fund actively builds a collaborative community of investors, entrepreneurs, researchers, and industry experts across Northern Ireland, the wider UK, and beyond. Through its network, the fund facilitates knowledge exchange, strategic guidance, and partnership opportunities to accelerate the growth and impact of its portfolio companies.

The fund engages its community through events such as investor meetings, spin‑out showcase days, entrepreneurship workshops, and innovation forums. These activities connect founders with specialist advisors, co‑investors, and potential commercial partners, enabling collaboration, operational support, and capacity building to strengthen the regional innovation ecosystem.

While QUBIS Innovation Fund’s investor base is centred on private individuals, Queen’s University alumni, and regional partners, it maintains transparent and regular communication with its network via updates, progress reports, and portfolio highlights. This promotes ongoing engagement and alignment with the fund’s mission to transform pioneering academic research into commercially viable businesses delivering societal and economic benefit.

By combining capital, expertise, and a connected community, QUBIS Innovation Fund empowers its portfolio companies and partners to create sustainable, high‑impact enterprises that contribute to a thriving knowledge‑based economy in Northern Ireland and the UK.

The Team

QUBIS Innovation Fund is led by a highly experienced group of professionals combining deep expertise in university technology commercialisation, early stage venture investment, and science based innovation. United by a shared commitment to scaling research-led businesses that deliver measurable societal and economic impact, the team provides strategic guidance and active partnership to portfolio companies across Northern Ireland, the wider UK, and beyond.

Leadership and Key Team Members:

  • Brian McCaul – Chief Executive Officer
    Brian has led QUBIS Ltd since 2014, overseeing the launch of the QUBIS Innovation Fund and positioning Queen’s University Belfast’s commercialisation arm among the leading university technology transfer offices in the UK. He brings extensive expertise in spin out creation, investment, and innovation ecosystem development. Brian is due to step down at the end of 2025, ensuring a smooth leadership transition.
  • Patrick Dewar – Portfolio Manager
    Patrick is responsible for managing, monitoring, and reporting on the performance of the QUBIS portfolio. A fellow of Chartered Accountants Ireland, he previously held senior roles in accountancy, banking, and corporate finance, including managing venture capital funds at Invest Northern Ireland.
  • David Moore – Head of Spin-Outs & Investments
    David oversees spin-out ventures and investments, bringing extensive experience of high-growth venture capital-backed businesses across technology sectors from formation through to exit. Prior to QUBIS, he worked with a regional development agency specialising in export-oriented technology companies and has a background as a systems engineer in the defence industry..
  • Louise Magee – Head of Marketing and Communications
    Louise leads communications strategy at QUBIS, supporting outreach and engagement with investors, entrepreneurs, and academic partners to enhance the profile and impact of QUBIS activities.
  • Anne Dornan – Investor Relations Manager
    Anne manages relationships with investors and supports fundraising and reporting processes to ensure transparent and effective communication with QUBIS’s capital providers.
  • Rob Blenkinsopp – Commercialisation Manager
    Rob focuses on commercialisation efforts, working closely with academics and entrepreneurs to translate research into viable business opportunities.
  • Vasudevan Krishnakumar – Technology Transfer Manager
    Vasu supports QUBIS’s technology transfer operations, helping protect and manage intellectual property and facilitating licensing and spin-out creation.
  • Julie Gormley – Operations Manager
    Julie oversees operational functions within QUBIS, ensuring smooth organisational performance and supporting strategic initiatives.

Additional Team Members:
QUBIS Innovation Fund is also supported by other investment managers, commercialisation specialists, and sector advisors with expertise in intellectual property, market analysis, and portfolio development. This multidisciplinary capability strengthens the fund’s ability to guide spin-outs from inception through to scale.

Learn more on the QUBIS Innovation Fund ‘Our People’ page.

FAQs

  1. What is QUBIS Innovation Fund’s investment strategy?
    QUBIS Innovation Fund focuses on early-stage investments in university spin-outs and research-led start-ups emerging from Queen’s University Belfast and partner institutions. The fund seeks ventures with innovative, research-based technologies addressing significant commercial and societal challenges. Its strategy targets pre-seed and seed stage companies that combine strong scientific foundations with credible business models to drive sustainable, long-term growth and measurable economic and societal impact.
  2. What sectors does QUBIS Innovation Fund invest in?
    QUBIS Innovation Fund invests across sectors leveraging deep technology and scientific expertise, prioritising companies with potential for high impact and commercial scalability. Key focus areas include life sciences and health technology, artificial intelligence and digital technologies, engineering and physical sciences, and sustainable growth with clean technologies aligned to net zero ambitions.
  3. What does QUBIS Innovation Fund look for in founders?
    The fund seeks visionary, research-driven founders and management teams with validated technologies and clear strategies for achieving product-market fit and scaling operations. Founders should demonstrate strong scientific or technological capability, operational expertise, and a commitment to delivering both commercial success and positive societal outcomes.
  4. What stage does QUBIS Innovation Fund invest in?
    QUBIS Innovation Fund primarily invests in early-stage companies at pre-seed and seed rounds, supporting ventures that have demonstrated a viable technology basis and are ready to progress towards market entry and initial scaling within the UK and Northern Ireland innovation ecosystem.
  5. What is the typical investment size?
    Investments typically range from £50,000 to £150,000 per company. QUBIS Innovation Fund usually takes minority equity positions, often acting as lead or co-investor, and provides strategic mentoring, operational support, and governance input to accelerate portfolio company growth and commercial success.

Contact

Are you a visionary entrepreneur developing a research led, tech enabled business with measurable societal or economic impact? Discover how QUBIS Innovation Fund can support your growth journey by providing early stage investment alongside strategic partnership. Visit QUBIS Innovation Fund Website.

Stay informed on the latest insights, portfolio updates, and investment opportunities by following QUBIS Innovation Fund on LinkedIn.

Explore more UK opportunities for greentech investment at Adopter’s Greentech Investors Map.

illustration of Earth